{
  "abstract": "Cryptococcus neoformans most commonly causes pulmonary and central nervous system infections, with skeletal involvement usually occurring as part of disseminated disease in profoundly immunocompromised hosts. We describe an HIV-negative man in his early 50s from South Africa with sarcoidosis, type 1 diabetes mellitus and chronic kidney disease who presented with a 1 month history of a localised swelling over the right anterior chest wall. CT demonstrated an expansile lesion of the right sixth anterior rib. Biopsy and culture confirmed C. neoformans with fluconazole non-susceptibility. The patient was treated with 12 months of voriconazole, achieving clinical and radiological resolution without surgical intervention.",
  "authors": [
    {
      "affiliations": [
        "Department of Infectious Diseases, Cork University Hospital, Cork, Ireland"
      ],
      "name": "Stephen P Connolly"
    },
    {
      "affiliations": [
        "Department of Infectious Diseases, Cork University Hospital, Cork, Ireland"
      ],
      "name": "Robert Shannon"
    },
    {
      "affiliations": [
        "Department of Respiratory Medicine, Cork University Hospital, Cork, Ireland"
      ],
      "name": "Anne O’Mahony"
    },
    {
      "affiliations": [
        "Department of Infectious Diseases, Cork University Hospital, Cork, Ireland"
      ],
      "name": "Arthur Jackson"
    }
  ],
  "title": "Cryptococcus neoformans causing localised osteomyelitis of the right anterior rib",
  "uid": "c687cd09-0842-51d3-b90a-949a16785129"
}