{
  "abstract": "A 64-year-old woman had fragility fractures which caused her to have gross deformities and confined her to bed. These were initially ascribed to vitamin D deficiency. However, despite correction of the deficiency, she did not improve. A review of previous records already showed glucosuria in the absence of diabetes, but this finding was overlooked. Eight years into the disease, it was realised that the glucosuria despite normal blood sugar could also mean that the patient was losing other substances needed for proper bone formation. Further investigations showed hypophosphataemia, renal phosphate wasting, hypokalaemia, mild metabolic acidosis, alkaline urine pH, hypouricaemia and aminoaciduria, all compatible with a proximal renal tubular defect (Fanconi syndrome). The fragility fractures were due to poor bone mineralisation because of hypophosphataemia induced by the inability of the kidneys to conserve phosphorus.",
  "authors": [
    {
      "affiliations": [
        "Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"
      ],
      "name": "Lilluck F Alacapa"
    },
    {
      "affiliations": [
        "Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines",
        "Department of Physiology, College of Medicine, University of the Philippines Manila, Manila, Philippines"
      ],
      "name": "Mark Anthony Santiago Sandoval"
    },
    {
      "affiliations": [
        "Section of Nephrology, Department of Medicine, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"
      ],
      "name": "Coralie Therese D Dimacali"
    },
    {
      "affiliations": [
        "Department of Orthopedics, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines"
      ],
      "name": "Nathaniel S Orillaza, Jr."
    }
  ],
  "title": "Glucosuria without diabetes: key to the diagnosis of fragility fractures due to Fanconi syndrome",
  "uid": "154a9354-8e61-5d4a-b665-00085aa70190"
}