{
  "abstract": "Hashimoto encephalopathy or steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is a rare condition associated with rapidly progressive dementia, stroke-like symptoms, psychosis and positive antithyroid antibodies. In this case report, a woman in her 80s with hypothyroidism and no other medically relevant history presented with a 2-week complaint of progressive hallucinations, short-term memory loss and paranoia. Eventually hospitalised, her hospital course was complicated by severe hospital-acquired delirium, which clouded the clinical picture; however, initial workup revealed an elevated thyroglobulin antibody and thyroid peroxidase, both highly specific for SREAT. A 3-day course of high-dose methylprednisolone (1 g/day) was administered, which revealed marked improvement in patient symptoms. Definitive treatment included a 13-week oral prednisone taper and outpatient follow-up with neurology and primary care. In cases of new onset neuropsychiatric symptoms in geriatric populations, SREAT is a reversible, must-not-miss diagnosis, when treated with systemic steroids.",
  "authors": [
    {
      "affiliations": [
        "Department of Family Medicine, Goshen Health, Syracuse, Indiana, USA"
      ],
      "name": "Mathew Wells"
    },
    {
      "affiliations": [
        "Department of General Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA"
      ],
      "name": "Jared Rife"
    },
    {
      "affiliations": [
        "Department of Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA"
      ],
      "name": "Samantha Hopkins"
    },
    {
      "affiliations": [
        "Department of Neurology, Goshen Health, Goshen, Indiana, USA"
      ],
      "name": "Elizabeth Nafziger"
    }
  ],
  "title": "Steroid-responsive encephalopathy associated with autoimmune thyroiditis",
  "uid": "8038eaf7-ed8c-5ad3-96a3-78f0705d87d4"
}
