{
  "abstract": "Surrogate outcomes may offer earlier evidence of benefit and initiate further evaluative work, but they cannot yet replace mortality as the definitive outcome in cancer screening trials, say Sian Taylor-Phillips and colleagues",
  "authors": [
    {
      "affiliations": [
        "Warwick Screening, Warwick Applied Health, Warwick Medical School, University of Warwick, Coventry, UK"
      ],
      "name": "Sarah Batson"
    },
    {
      "affiliations": [
        "Cancer Research UK and UCL Cancer Trials Centre, Cancer Institute, University College London, UK"
      ],
      "name": "Allan Hackshaw"
    },
    {
      "affiliations": [
        "UK National Screening Committee Secretariat, Department of Health and Social Care, London, UK"
      ],
      "name": "Anne Mackie"
    },
    {
      "affiliations": [
        "UK National Screening Committee Secretariat, Department of Health and Social Care, London, UK"
      ],
      "name": "Mike Richards"
    },
    {
      "affiliations": [
        "UK National Screening Committee Secretariat, Department of Health and Social Care, London, UK"
      ],
      "name": "Rosalind Given-Wilson"
    },
    {
      "affiliations": [
        "Warwick Screening, Warwick Applied Health, Warwick Medical School, University of Warwick, Coventry, UK"
      ],
      "name": "Emma Atakpa"
    },
    {
      "affiliations": [
        "Warwick Screening, Warwick Applied Health, Warwick Medical School, University of Warwick, Coventry, UK"
      ],
      "name": "Edmund Njeru Njagi"
    },
    {
      "affiliations": [
        "Warwick Screening, Warwick Applied Health, Warwick Medical School, University of Warwick, Coventry, UK"
      ],
      "name": "Bethany Shinkins"
    },
    {
      "affiliations": [
        "University of Cambridge, Cambridge, UK"
      ],
      "name": "Tom Callender"
    },
    {
      "affiliations": [
        "Institute of Health Research, University of Exeter Medical School, University of Exeter, Exeter, UK"
      ],
      "name": "Chris Hyde"
    },
    {
      "affiliations": [
        "UK National Screening Committee Secretariat, Department of Health and Social Care, London, UK"
      ],
      "name": "Cristina Visintin"
    },
    {
      "affiliations": [
        "UK National Screening Committee Secretariat, Department of Health and Social Care, London, UK"
      ],
      "name": "David Thompson"
    },
    {
      "affiliations": [
        "Public representative, Adult Reference Group, UK National Screening Committee, Department of Health and Social Care, London, UK"
      ],
      "name": "Eleanor Cozens"
    },
    {
      "affiliations": [
        "Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK"
      ],
      "name": "D Gareth Evans"
    },
    {
      "affiliations": [
        "Institute of Applied Health Research, University of Birmingham, Birmingham, UK"
      ],
      "name": "Karla Hemming"
    },
    {
      "affiliations": [
        "Division of Population Health, Health Services Research and Primary Care, The University of Manchester, UK"
      ],
      "name": "Katherine Payne"
    },
    {
      "affiliations": [
        "UCL Centre for Medical Imaging, Division of Medicine, Rayne Institute, London, UK"
      ],
      "name": "Steve Halligan"
    },
    {
      "affiliations": [
        "Warwick Screening, Warwick Applied Health, Warwick Medical School, University of Warwick, Coventry, UK"
      ],
      "name": "Sian Taylor-Phillips"
    }
  ],
  "title": "UK National Screening Committee position statement on surrogate outcomes in cancer screening trials",
  "uid": "896caa67-ae0a-5478-9ab7-2447b2efa521"
}