{
  "abstract": "Six years ago, a trial from Spain reported that people taking antihypertensive medication at bedtime had better blood pressure control and only half the number of cardiovascular events when compared with people taking their drugs in the morning ( Eur Heart J 2019 doi:10.1093/eurheartj/ehz754). Many commentators thought that the apparent benefits were implausibly large—a view which was supported by a later trial that found no advantage from nocturnal dosing (Lancet 2022 doi:10.1016/S0140-6736(22)01786-X). Settling any remaining doubt, a large trial in Canadian primary care finds that bedtime administration of antihypertensive medications has no beneficial effect on deaths or major cardiovascular events (JAMA doi:10.1001/jama.2025.4390).",
  "authors": [
    {
      "affiliations": [],
      "name": "British Medical Journal Publishing Group"
    }
  ],
  "title": "Healing without scarring . . . and other stories",
  "uid": "28d56c55-cb2b-519d-875e-1e3dce14d11f"
}