{
  "abstract": "Aims To evaluate prevalence, types and biometric predictors of peripheral retinal lesions in highly myopic children.Methods Retrospective cross-sectional study at a tertiary centre. Participants were aged 4–17 years with high myopia (≤−4.00 dioptres (D) at 4–6 years; ≤−6.00 D at 7–17 years). Peripheral retina was assessed by ultra-widefield imaging (UWF) and/or documented dilated ophthalmoscopy.Results We analysed 160 eyes from 89 children (mean age 10.4±3.8 years; mean spherical equivalent −9.95±3.59 D; mean axial length (AL) 26.68±1.82 mm). Peripheral lesions were present in 87/160 eyes (54.4%), more frequent in 7–17-year-olds than in 4–6-year-olds (59.4% vs 34.4%) (p<0.05). Among affected eyes, 50/87 (57%) had a single lesion and 37/87 (43%) multiple; multiplicity increased with age (p<0.001). The most frequent lesions were dark without pressure (46/160; 28.7%), white without pressure (32/160; 20.0%), snail-track degeneration (15/160; 9.4%), microcystoid degeneration (11/160; 6.9%) and lattice degeneration (10/160; 6.3%). In multivariate models, AL was the strongest independent predictor of both lesion prevalence (OR=1.45; 95% CI 1.07 to 2.03; p=0.021) and multiplicity (OR=2.17; 95% CI 1.53 to 3.07; p<0.001). Model-derived lesion probability reached 50% at AL 26.2 mm and 80% at 29.4 mm.Conclusions Peripheral retinal lesions are common in paediatric high myopia and related strongly to AL. Early peripheral retinal assessment using UWF imaging or thorough dilated examination may enhance risk stratification and surveillance.",
  "authors": [
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Jacques Bijon"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Louise Brach"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Etienne Boulanger"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Ismael Chehaibou"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Aude Couturier"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France",
        "Department of Ophthalmology, Heidelberg University Hospital, Heidelberg, Germany"
      ],
      "name": "Songhomitra Panda-Jonas"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Youssef Abdelmassih"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Sophie Bonnin"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France"
      ],
      "name": "Georges Caputo"
    },
    {
      "affiliations": [
        "French Institute of Myopia, Adolphe de Rothschild Foundation Hospital, Paris, France",
        "CRESS, Obstetric, Perinatal, Paediatric Life Course Epidemiology Research Team, OPPaLE, INSERM, INRAE, Université Paris Cité, Paris, France"
      ],
      "name": "Thibaut Chapron"
    }
  ],
  "title": "Peripheral retinal lesions in highly myopic children: prevalence, types and biometric correlates",
  "uid": "553cb404-d57c-5aeb-9bcb-a178fdd9e060"
}