{
  "abstract": "From ancient times until as late as 1897, the management of nocturnal enuresis in childhood had been a series of untestable interventions, loosely categorised into the homeopathic or humour era of medieval medicine to mechanical treatments in Victorian times.1 Meatotomy, circumcision, urine alkalinisation, electric currents, injections of ergot or strychnine, brutal local application of various chemical irritants or just shaming and public humiliation have all been tried and historically documented by Holt2 in his seminal textbook. This was in a time without widespread use of anaesthesia. A case series 100 years ago, was published in this journal, of sixty cases from a London children’s hospital successfully treated with a standardised bundle of multi-modal interventions.3 Although the physiological and pharmacological understanding of nocturnal enuresis was still decades in the future, there was a remarkable resemblance to what best practice looks like today.4",
  "authors": [
    {
      "affiliations": [
        "Great North Children’s Hospital, Newcastle Upon Tyne, UK"
      ],
      "name": "Yincent Tse"
    }
  ],
  "title": "Management of nocturnal enuresis: changes over a century",
  "uid": "6e81613d-8b50-56fe-97c1-4c9849fca483"
}