{
  "abstract": "The third British Paediatric Surveillance Unit (BPSU) survey of herpes simplex virus (HSV) infection in infants presenting before 90 days of age, reported in this edition of Archives, informs us that the annual UK incidence has tripled over the last 25 years. However, this remains a rare condition (6 per 100 000 live births), and most paediatricians/neonatologists will see less than a handful of cases in their working life.1 During the same time period, routine laboratory data from the UK Health Security Agency reports double the incidence (13.7/100 000 births), suggesting under-reporting to the BPSU survey. This also reflects the concomitant increasing national incidence of sexually transmitted infections (Sexually transmitted infections and screening for chlamydia in England: 2024 report - GOV.UK). Despite its rarity, neonatal HSV remains a very important condition due to its persistently high mortality and morbidity.",
  "authors": [
    {
      "affiliations": [
        "Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK"
      ],
      "name": "Hermione Lyall"
    }
  ],
  "title": "Infants at highest risk of herpes simplex virus disease who should start immediate empiric aciclovir",
  "uid": "f4e67756-9c2f-5c32-a115-7baa03e4abfb"
}