{
  "abstract": "Objective To investigate real-life salbutamol use by children with asthma at home and compare it with their written asthma action plans (WAAPs).Design Multicentre, observational prospective study.Setting Five tertiary care hospitals in France.Patients 120 children aged 3–11 years with asthma.Interventions Parents used a smartphone application connected to a smart inhaler via Bluetooth to record salbutamol use and answer questionnaires about their child’s asthma symptoms over 6 months.Main outcome measures The primary outcome was the median number of salbutamol puffs used in the first 2 hours after an asthma symptom occurred, depending on symptom type. Secondary outcomes included how families operationalised WAAP instructions and the proportion who administered more or less salbutamol than prescribed.Results 43 families used the smart inhaler for asthma symptoms, recording 124 episodes of salbutamol use. The median number of puffs used in the first 2 hours was 3 (IQR 2–4, range 1–26), varying between 2 and 4 depending on the initial symptom type. The number of puffs used did not differ significantly between episodes with and without symptom resolution. 18 (42%) families used a number of salbutamol puffs similar to that in their WAAP, while 21 (49%) used fewer and only 4 (9%) used more.Conclusions Families typically use 2–4 puffs of salbutamol in the first 2 hours after an asthma symptom. Adjusting WAAPs to start with 2–4 puffs of salbutamol, to be repeated if necessary, would be more in line with family practice, and effective in most situations.Trial registration number NCT04810169.",
  "authors": [
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France"
      ],
      "name": "Apolline Gonsard"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, Hôpitaux Pédiatriques de Nice CHU-LENVAL, Nice, France"
      ],
      "name": "Lisa Giovannini-Chami"
    },
    {
      "affiliations": [
        "Department of Paediatrics, University and Regional Hospital Centre Brest, Brest, Bretagne, France"
      ],
      "name": "Pierrick Cros"
    },
    {
      "affiliations": [
        "CHU Limoges, Limoges, Nouvelle-Aquitaine, France"
      ],
      "name": "Alexandra Masson"
    },
    {
      "affiliations": [
        "CHU Limoges, Limoges, Nouvelle-Aquitaine, France"
      ],
      "name": "Celine Menetrey"
    },
    {
      "affiliations": [
        "Lille University Hospital, Lille, Hauts-de-France, France"
      ],
      "name": "Clémence Mordacq"
    },
    {
      "affiliations": [
        "Lille University Hospital, Lille, Hauts-de-France, France"
      ],
      "name": "Camille Cisterne"
    },
    {
      "affiliations": [
        "University Hospital Ambroise Paré, AP-HP, Paris, France"
      ],
      "name": "Johan Personnic"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France"
      ],
      "name": "Charlotte Roy"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France"
      ],
      "name": "Clément Poirault"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France"
      ],
      "name": "Rola Abou Taam"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France",
        "Université Paris Cité, Paris, France"
      ],
      "name": "Alice Hadchouel"
    },
    {
      "affiliations": [
        "Clinical Research Unit, University Hospital Necker-Enfants Malades, Paris, France"
      ],
      "name": "Alexandra Pirojoc"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France",
        "Université Paris Cité, Paris, France"
      ],
      "name": "Christophe Delacourt"
    },
    {
      "affiliations": [
        "Department of Pediatric Pulmonology and Allergology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France",
        "Université Paris Cité, Paris, France",
        "Department HeKA Inserm UMR 1138, Centre de Recherche des Cordeliers, Paris, France"
      ],
      "name": "David Drummond"
    }
  ],
  "title": "Home use of short-acting beta agonists by children with asthma: a multicentre digital prospective study",
  "uid": "0b022077-0bbd-5fca-86ee-01d4279ac62a"
}